Kodiak Sciences Announces Upcoming Presentation of KSI-301 (tarcocimab tedromer) Clinical Data and Antibody Biopolymer Conjugate Development Programs at the Angiogenesis, Exudation and Degeneration 2023 Virtual Meeting
Details of the presentation are as follows:
Title: Update on KSI-301 (tarcocimab tedromer) and Antibody Biopolymer Conjugate Development Programs
Presenter: Diana V. Do, M.D., Professor of Ophthalmology, Vice Chair of Clinical Affairs,
Presentation date and time: February 11, 2023;
"We continue to make strong progress executing multiple trials across the tarcocimab (KSI-301) clinical program. We anticipate four Phase 3 clinical study readouts later this year, in approximately 3Q2023. Building on the unique durability shown in BEACON, our positive Phase 3 study in retinal vein occlusion where we doubled the treatment interval for all patients, we look forward to the results across the broader Phase 3 program in which we explore 5- and 6- month durability in patients with diabetic eye disease," said
"We are also pleased to have successfully opened the IND for KSI-501, our second product candidate built from the
Kodiak plans to post the presentation slides on the "Events and Presentations" section of Kodiak's website at http://ir.kodiak.com/ at the beginning of the presentation.
About tarcocimab tedromer (KSI-301)
Tarcocimab tedromer is an investigational anti-VEGF therapy built on Kodiak's Antibody Biopolymer Conjugate (ABC) Platform and is designed to maintain potent and effective drug levels in ocular tissues for longer than existing available agents. Kodiak's objective with tarcocimab tedromer is to develop a new first-line agent to improve outcomes for patients with retinal vascular diseases and to enable earlier treatment and prevention of vision loss for patients with diabetic eye disease. The tarcocimab tedromer clinical program is designed to assess the product's durability, efficacy and safety in several major retinal vascular diseases in parallel, through the DAYLIGHT study in wet AMD, the GLEAM and GLIMMER studies in DME, the BEACON study in RVO and the GLOW study in non-proliferative DR (without DME). The global tarcocimab tedromer clinical program is being conducted at 150+ study sites in more than 10 countries. Kodiak is developing and owns global rights to tarcocimab tedromer.
Also built on Kodiak's Antibody Biopolymer Conjugate (ABC) Platform, KSI-501 is an investigational, potential first-in-class bispecific
Kodiak (Nasdaq: KOD) is a biopharmaceutical company committed to researching, developing and commercializing transformative therapeutics to treat high prevalence retinal diseases. Founded in 2009, we are focused on bringing new science to the design and manufacture of next generation retinal medicines to prevent and treat the leading causes of blindness globally. Our ABC Platform™ uses molecular engineering to merge the fields of antibody-based and chemistry-based therapies and is at the core of Kodiak's discovery engine. Kodiak's lead product candidate, tarcocimab tedromer, is a novel anti-VEGF antibody biopolymer conjugate being developed for the treatment of retinal vascular diseases including wet age-related macular degeneration, the leading cause of blindness in elderly patients in the developed world, and diabetic eye diseases, the leading cause of blindness in working-age patients in the developed world. Kodiak has leveraged its ABC Platform to build a pipeline of product candidates in various stages of development. KSI-501 is our dual inhibitor antibody biopolymer conjugate targeting both VEGF (VEGF-trap) and IL-6 (anti-IL-6 antibody) for the treatment of retinal diseases. We are expanding our early research pipeline to include ABC Platform based triplet inhibitors for multifactorial retinal diseases such as dry AMD and glaucoma. Kodiak is based in
Kodiak®, Kodiak Sciences®, ABC™, ABC Platform™ and the Kodiak logo are registered trademarks or trademarks of
This release contains "forward-looking statements" within the meaning of Section 27A of the Securities Act of 1933, Section 21E of the Securities Exchange Act of 1934 and the Private Securities Litigation Reform Act of 1995. These forward-looking statements are not based on historical fact and include statements regarding: the expected timing of clinical study readouts; the potential benefits of KSI-501, including its potential to be a first-in-class bispecific
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John Borgeson, Senior Vice President and Chief Financial Officer, (650) 281-0850, email@example.com